Bacterial cellulose (BC), produced by microorganisms such as Komagataeibacter xylinus, is used in wound healing applications due to its material properties, including the ability to maintain high-water content and good biocompatibility. Moreover, BC also presents regular network structure (typical crystalline form of cellulose Iα), which provides flexible material property and high strength. Numerous BC dressing studies are being investigated to improve wound healing characteristics through usage of different cultivation systems and surface modification of BC. Development of an ideal wound dressing to efficiently improve wound healing process is an important issue in wound care. The present study aims to cross-link dextran with bacterial cellulose (BC) to form a dextran/BC hydrogel, and to evaluate the performance of dextran-modified BC hydrogel in a mouse model. This is the first report to apply dextran/BC hydrogel as wound dressing. Our results indicated that the modified dressing - dextran/BC hydrogel - appears to contain a high-water content, rigid but flexible material properties, fine cell proliferation with non-cytotoxicity at the cell-based level, and excellent wound healing ability in vivo. The added dextran plays a key role in that it promotes fibroblast cell growth in the proliferation stage and also help skin maturation in the remodeling stage, causing the acceleration of the wound healing process. It is important to note that this is superior to the commercial wound dressings. Human studies are needed to further investigate the applications as a therapy for different types of wounds.

It is a great pleasure and an honor to extend to you a warm welcome to The International Conference on Life Science & Biological Engineering.

Fukuoka is an exceptional location for the conference. Fukuoka is an easy place to visit—it is connected closely to all major airports of Japan, and has direct flights to Seoul, Dalian, Shanghai, Hong Kong, Taipei, Singapore, and Honolulu. Fukuoka Airport is the fourth busiest airport in Japan. Reached in just five minutes by subway from Hakata Station, it is also one of the most centrally located airports in the country.

Fukuoka was the very first place in Japan that received people from the continent in the first century, and still its local people are lively and kind. Its seafood is often considered the best in Japan.

Fukuoka is one of the oldest places of Japan with very modern parts. Fukuoka city and its neighborhood have many attractive places to visit. On Wednesday, we will have a socializing tour as well. We hope you will join us and take a little extra time to enjoy the spectacular and unique beauty of this region.

Hoping to meet you in Fukuoka!

ADD 〒812-0027 Hakata Riverain 3-2 Shimokawabata-machi, Hakata-ku, Fukuoka
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